Guy Manoukian started to play piano at the age of four, when he started studying classical music. He first appeared on television at the age of 6; he was invited to play in the Lebanese presidential palace at the age of 7 and composed music at the age of 8, winning his first competition. He started performing professional concerts in 1997. He also played basketball in the Lebanese Basketball League. He put out his album "Guy Manoukian - Live in Cairo" in 2006.